Publications

blue & bold — Rogala Lab member
Ψ — equal contribution
@ — corresponding author

Structure of the nutrient-sensing hub GATOR2

Max L ValensteinΨ@, Kacper B RogalaΨ@, Pranav V. Lalgudi, Edward J Brignole, Xin Gu, Robert A Saxton, Lynne Chantranupong, Jonas Kolibius, Jan-Philipp Quast, David M Sabatini.

Nature. 607(7919):610-616. 2022 July 13.

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Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex.

Kuang ShenΨ, Kacper B RogalaΨ, Hui-Ting Chou, Rick K Huang, Zhiheng Yu, David M Sabatini

Cell. 179(6):1319-1329.e8. 2019 November 27.

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Structural basis for the docking of mTORC1 on the lysosomal surface.

Kacper B Rogala, Xin Gu, Jibril F Kedir, Monther Abu-Remaileh, Laura F Bianchi, Alexia M S Bottino, Rikke Dueholm, Anna Niehaus, Daan Overwijn, Ange-Célia Priso Fils, Sherry X Zhou, Daniel Leary, Nouf N Laqtom, Edward J Brignole, David M Sabatini.

Science. 366(6464):468-475. 2019 October 25.

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Architecture of human Rag GTPase heterodimers and their complex with mTORC1.

Madhanagopal Anandapadamanaban, Glenn R Masson, Olga Perisic, Alex Berndt, Jonathan Kaufman, Chris M Johnson, Balaji Santhanam,
Kacper B Rogala, David M Sabatini, Roger L Williams.

Science. 366(6462):203-210. 2019 October 11.

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Interaction between the Caenorhabditis elegans centriolar protein SAS-5 and microtubules facilitates organelle assembly.

Sarah BianchiΨ, Kacper B RogalaΨ, Nicola J DynesΨ, Manuel Hilbert, Sebastian A Leidel, Michel O Steinmetz, Pierre Gönczy, Ioannis Vakonakis.

Molecular Biology of the Cell. 29(6):722-735. 2018 March 15.

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Cross-linking mass spectrometry identifies new interfaces of Augmin required to localise the γ-tubulin ring complex to the mitotic spindle.

Jack W C Chen, Zhuo A Chen, Kacper B Rogala, Jeremy Metz, Charlotte M Deane, Juri Rappsilber, James G Wakefield.

Biology Open. 6(5):654-663. 2017 May 15.

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Probing the solution structure of IκB kinase (IKK) subunit γ and its interaction with Kaposi sarcoma-associated herpes virus Flice-interacting protein and IKK subunit β by EPR spectroscopy.

Claire Bagnéris, Kacper B Rogala, Mehdi Baratchian, Vlad Zamfir, Micha B A Kunze, Selina Dagless, Katharina F Pirker, Mary K Collins, Benjamin A Hall, Tracey E Barrett, Christopher W M Kay.

Journal of Biological Chemistry. 290(27):16539-49. 2015 July 3.

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Misato controls mitotic microtubule generation by stabilizing the TCP-1 Tubulin chaperone complex.

Valeria Palumbo, Claudia Pellacani, Kate J Heesom, Kacper B Rogala, Charlotte M Deane, Violaine Mottier-Pavie, Maurizio Gatti, Silvia Bonaccorsi, James G Wakefield.

Current Biology. 25(13):1777-83. 2015 June 29.

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The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation.

Kacper B Rogala, Nicola J Dynes, Georgios N Hatzopoulos, Jun Yan, Sheng Kai Pong, Carol V Robinson, Charlotte M Deane, Pierre Gönczy, Ioannis Vakonakis.

eLife. 4:e07410. 2015 May 29.

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Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.

Georgios N Hatzopoulos, Michèle C Erat, Erin Cutts, Kacper B Rogala, Leanne M Slater, Philip J Stansfeld, Ioannis Vakonakis@.

Structure. 21(11):2069-77. 2013 November 5.

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